Aquatic Toxicity of Pinacolyl Alcohol

Abstract

The aquatic toxicity of a secondary alcohol, 3,3-dimethyl-2-butanol Pinacolyl Alcohol (PA), was determined. Acute tests were conducted on Pimephales promelas, 48 hr EC50 = 443.1 mg PA/1, and Daphnia magna, 24 hr EC50 = 513.2 mg PA/1. Growth inhibition tests (96 hr) were conducted using Ankistrodesmus falcatus, EC50 = 257.7 mg PA/1. In general, the toxicity of straight-chained alcohols increases proportionally with the molecular weights. Using the structure activity equation (Log EC50 = 1.10 (LogP) + 0.05 (LogP)squared - 1.22) for P. promelas, the calculated toxicity of PA (EC50 = 547.0 mg/1) agrees with experimental determinations.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1986
Accession Number
ADA173604

Entities

People

  • Dennis W. Johnson
  • Mark V. Haley
  • Wayne G. Landis
  • William T. Muse

Organizations

  • Edgewood Chemical Biological Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alcohols
  • Algae
  • Aquatic Organisms
  • Bioassay
  • Cell Count
  • Cells
  • Classification
  • Data Analysis
  • Detectors
  • Engineering
  • Environmental Protection
  • Factor Analysis
  • Fish
  • Gas Chromatography
  • Molecular Weight
  • Security
  • Toxicity

Readers

  • Aquatic Ecology
  • Organizational Psychology.
  • Quantum Chemistry