Geometric Universality in Brain Allosteric Protein Dynamics: Complex Hydrophobic Transformation Predicts Mutual Recognition by Polypeptides and Proteins,

Abstract

A relationship is derived between the thermodynamic entropy-enthalpy compensation of proteins and hyperbolic dynamics of their resting, signal-sensitive behavior. This formulation is then used to derive a hydrophobic sequence code which successfully predicts structure and function in a variety of polypeptide hormones.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1986
Accession Number
ADA175398

Entities

People

  • Arnold J. Mandell
  • Barbara W. Blomgren
  • Patrick V. Russo

Organizations

  • University of California, San Diego

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acquired Immune Deficiency Syndrome
  • Amino Acids
  • Cells
  • Chemical Reactions
  • Computational Science
  • Difference Equations
  • Differential Equations
  • Equations
  • Free Energy
  • Geometry
  • Growth Factors
  • Lymphocytes
  • Numerical Analysis
  • Peptide Growth Factors
  • Peptides
  • Phase Transformations
  • Proteins

Fields of Study

  • Chemistry

Readers

  • Calculus or Mathematical Analysis
  • Computational Modeling and Simulation
  • Molecular and Cellular Biochemistry