Effects of Infection on Oxygen Consumption and Core Temperature in Experimental Thermal Injury

Abstract

Oxygen consumption VO2 and colonic temperature T sub C measured in groups of rats before and after 30% total body surface, full thickness burns. Some wounds were seeded with Pseudomonas aeruginosa or Staphylococcus epidermidis, and some seeded wounds were treated with SULFAMYLON or SILVADENE. Three groups became bacteremic (B) during the 2-3 week period of observation. The metabolic cost of wound contamination appeared to vary with bacterial strain. The metabolic effects of infection appeared to vary with bacterial strain. The metabolic effects of infection appear to be a continuum, beginning with a modest rise in VO2 and progressing to greater increases in VO2 and T sub C with wound invasion and systemic infection.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1986
Accession Number
ADA175666

Entities

People

  • Albert T. Mcmanus
  • Arthur D. Mason Jr.
  • Basil A. Pruitt Jr.
  • Louis H. Aulick

Organizations

  • United States Army Institute of Surgical Research

Tags

DTIC Thesaurus Topics

  • Animals
  • Anti-Infective Agents
  • Body Weight
  • Burns
  • Data Analysis
  • Dermatologic Agents
  • Environment
  • Hypermetabolism
  • Infection
  • Information Science
  • Laboratory Animals
  • Mass Spectrometers
  • Mass Spectrometry
  • Measurement
  • Metabolism
  • Regression Analysis
  • Wound Infections

Readers

  • Materials Science and Engineering.
  • Microbial Pathology
  • Trauma Surgery or Emergency Medicine.