Development of Central Nervous System Radioprotectors.
Abstract
This project is attempting to develop practical drugs which would be able to protect the central nervous system from acute functional injury produced by ionizing radiation. By 'practical' is meant drugs which could be self administered and which do not, by themselves, alter the functional capacity of the central nervous system. Thusfar, at least one true CNS radioprotector has been identified, and simple chemical tests have been developed which allow identification of those chemical properties which should allow CNS protection. Keywords: radioprotection; phosphorothioates; radiation protection; radioprotective agents; lipophilic; NSC-62857; pseudoureas; WR-2529; sulfonates; WR-2721.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1983
- Accession Number
- ADA177829
Entities
People
- John M. Yuhas