Development of Central Nervous System Radioprotectors.

Abstract

This project is attempting to develop practical drugs which would be able to protect the central nervous systems from acute functional injury produced by ionizing radiation. By 'practical' is meant drugs which could be self administered and which do not, by themselves, alter the functional capacity of the central nervouse system. Assays are being developed which allow quantitation of functional injury and preliminary identification of appropriate candidate drugs is underway. Keywords: radioprotection; radioprotective agents; WR-2721.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1982
Accession Number
ADA177831

Entities

People

  • John M. Yuhas

Organizations

  • Children's Hospital of Philadelphia

Tags

DTIC Thesaurus Topics

  • Albumins
  • Blood
  • Blood Cells
  • Blood-Brain Barrier
  • Bone Marrow
  • Brain
  • Central Nervous System
  • Health Services
  • Hydrophilic Properties
  • Hydroxides
  • Ionizing Radiation
  • Medical Personnel
  • Nervous System
  • Radiation
  • Radiation Injuries
  • Radiation Protection
  • Task Performance And Analysis

Readers

  • Systems Analysis and Design
  • Toxicology/Environmental Toxicology