Studies on Typhus and Spotted Fever.

Abstract

This multifaceted research program was a planned coordinated program in which the individual components were designed to converge ultimately on the militarily significant mission of improved methods for the prevention, control and treatment of rickettsial diseases. Studies were concentrated primarily on typhus group rickettsiae, but some observations were made on spotted fever and scrub typhus group organisms and on Rochalimaea quintana as well. These included, but were not limited to, the development of modern quantitative methodology and studies on the biology of the infection cycle, basis for immunity in typhus so that immunological requirements of vaccines could be defined, analysis of surface components of typus organisms that might be involved in protective immunity, elementary genetics and chemotherapy. Keywords: Louse-borne; Antigens; Growth cycle.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1986
Accession Number
ADA177998

Entities

People

  • Charles L. Wisseman Jr.

Organizations

  • University of Maryland, Baltimore

Tags

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacteria
  • Blood
  • Cell Membrane
  • Cells
  • Chemistry
  • Chemotherapy
  • Genetics
  • Immune Serums
  • Immunity
  • Infection
  • Lymphatic System
  • Medical Personnel
  • Microbiology
  • Rodents
  • Scrub Typhus

Readers

  • Infectious Disease/Epidemiology
  • Neurodegenerative Parkinson's Disease and Rickettsial Disease handbook, including the data level of dopamine, BC, neurons, and PD.
  • Systems Analysis and Design

Technology Areas

  • Biotechnology