Lassa Fever Immune Plasma.

Abstract

Prevention of Lassa Fever requires elucidation of its epidemiology, and will likely require the preparation and use of a vaccine. However, investigations in to Lassa Virus infection carry a definite risk, and measures should be available to protect investigators as well as patients. Thus, reasearch into the epidemiology and pathogenesis of LF, in the nature of the virus, and in the development of a preventive vaccine appear to be of high priority if this hemorrhagic fever is to be brought under control. Plasma donors were identified by continued serological testing of febrile patients in hospitals, and by attempts at virus isolation. Potential donors were requested to submit sera for testing for LV NA, and those with adequate LNI were asked to submit to plasmapheresis. Epidemiologicalinvestigations were carried out among patients found to have LF; villages were selected for differences that might elucidate factors contributing to varying prevalences of LVA. Keywords: Arboviruses.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1986
Accession Number
ADA180344

Entities

People

  • John D. Frame

Organizations

  • Columbia University

Tags

DTIC Thesaurus Topics

  • Age Groups
  • Biomedical Research
  • Blood
  • Families (Human)
  • Health Services
  • Infectious Diseases
  • Lassa Fever
  • Medical Personnel
  • Mycobacterium Infections
  • New York
  • Physicians
  • Public Health
  • Serodiagnosis
  • Students
  • United States
  • Virus Diseases

Fields of Study

  • Medicine

Readers

  • Systems Analysis and Design
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology