Cardiopulmonary Effects of Stressful Exercise at Altitude (4,000 Feet) of Individuals with Sickle Cell Trait (HbAS or SCT).
Abstract
Although generally regarded as a benign condition, controversy persists over the question of whether individuals with Sickle Cell Trait (SCT) are at greater risk for sudden unexplained death (SUD) and other medical complications resulting from strenuous exercise, especially at altitude. In order to establish whether physiologic changs associated with strenuous exercise at altitude (namely hypoxia, dehydration, and acidosis) may individually or in combination adversely affect similarly engages individuals with SCT, the cardiopulmonary response to acute strenuous exercise at 4,000 ft was evaluated in healthy, male nonacclimatized basic trainee volunteers with SCT (n=25) and non-SCT (n=16) controls. There were no discernible clinical differences in exercise performance between the SCT and the control volunteers. Keywords: Blood diseases; Blood chemistry; Exercise (physiology); Stress physiology; Sickle cell anemia.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 18, 1985
- Accession Number
- ADA180808
Entities
People
- Idelle M. Weisman
- R. J. Zeballos