The Physiological Basis of a Theory for Synapse Modification.

Abstract

The functional organization of the cerebral cortex is modified dramatically by sensory experience during early postnatal life. The basis of these modifications is a type of synaptic plasticity that may also contribute to some forms of adult learning. The question of how synapses modify according to experience has been approached by determining theoretically what is required of a modification mechanize to account for the available experimental data in the developing visual cortex. The resulting theory states precisely how certain variables might influence synaptic modifications. this insight has led to the development of a biologically plausible molecular model for synapse modification in the cerebral cortex.

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Document Details

Document Type
Technical Report
Publication Date
Jun 29, 1987
Accession Number
ADA182184

Entities

People

  • Ford F. Ebner
  • Leon Cooper
  • Mark Bear

Organizations

  • Brown University

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Acidic Amino Acids
  • Amino Acids
  • Brain
  • Cells
  • Cellular Structures
  • Cerebral Cortex
  • Firing Rate
  • Glutamates
  • Glutamic Acid
  • Mathematical Analysis
  • Medical Personnel
  • Nervous System
  • Neural Networks
  • Neurons
  • New York
  • Universities
  • Visual Cortex

Fields of Study

  • Biology

Readers

  • Neuroscience
  • Theoretical Analysis.