Treatment of Laser Induced Retinal Injuries.

Abstract

The effect of argon laser irradiation of the retina at various energy levels on PGE2 production by the retina-choroid, and PGE2 and protein accumulation in the vitreous cavity, was investigated and compared to the effects of sham exposures. The effect of steroid treatment on PGE2 levels following laser exposure was also examined. Results showed that both single and multiple suprathreshold applications were characterized by a biphasic increase in retinal PGE2 production, whereas multiple subthreshold exposure elicited an increase in PGE2 production of much longer duration. In eyes subjected to sham exposure, the increase in retinal PGE2 production was evident as a single peak. Moreover laser-induced retinal burns at most of the energy levels studied, as well as sham exposure resulted in a accumulation of PGE2 and/or protein in the vitreous body. Keywords: Prostaglanidn; Vitreal protein levels.

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Document Details

Document Type
Technical Report
Publication Date
Apr 02, 1986
Accession Number
ADA183725

Entities

People

  • Michael Belkin
  • Nava Naveh

Organizations

  • Tel Aviv University

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Animals
  • Argon Lasers
  • Availability
  • Biomedical Research
  • Energy Levels
  • Eye
  • Illumination
  • Intervals
  • Laboratory Animals
  • Laser Applications
  • Laser Safety
  • Lasers
  • Prostaglandin
  • Scientific Literature
  • Time Intervals
  • Universities

Readers

  • Cardiovascular Physiology
  • Vision Science/Vision Psychology/Cognitive Neuroscience.

Technology Areas

  • Directed Energy