Facile Synthesis of Alpha-Deuterated Acrylics and Activated Vinyls.

Abstract

A simple, direct exchange reaction has been discovered for vinyl groups in which the exchangeable deuterium of alcohols (e.g. CH3OD) or water (D2O) replaces only the alpha-hydrogen of activated vinyls under catalysis by DABCO (1,4-diazabicylo-(2.2.2.) octane). Acrylate esters, acrylonitrile, acrylamides and methyl vinyl ketone were found to go rapid exchange at room temperature to give easily isolated, pure and readily polymerizable alpha-deuterated compounds. This procedure is the most general efficient and cost-effective one available for obtaining such isotopically labeled materials.

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Document Details

Document Type
Technical Report
Publication Date
Aug 27, 1987
Accession Number
ADA184207

Entities

People

  • Lon J. Mathias
  • Ronald F. Colletti

Organizations

  • University of Southern Mississippi

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Acrylates
  • Alkenes
  • Chemical Reactions
  • Classification
  • Department Of Defense
  • Deuterium
  • Exchange Reactions
  • Governments
  • Military Research
  • Mississippi
  • Monitoring
  • Security
  • Spectra
  • United States
  • United States Government
  • Universities

Fields of Study

  • Chemistry

Readers

  • Organic Chemistry
  • Polymer Science and Technology