Mainframe Computer Programs for Rapid Analysis of Hybridoma Screening Data.

Abstract

Most laboratories that currently produce large numbers of hybridomas grow them and screen their media by immunoassay in 96-well plates. Robotic systems are commercially available for sterile sampling, feeding and expansion of hybridomas. We have written a program package in microsoft Pascal that converts the records for a Dynatech Autoprep automated hybridoma sampler and a Flow, Multiskan enzyme immunoassay reader to an ASCII database format, merges them, and creates tables which can be sorted by any parameter (eg. source plate/well, target plate/well, or assay result) and a histogram from which the best responding hybridomas can be selected.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1985
Accession Number
ADA184235

Entities

People

  • Alexander E. Karu
  • Andrew M. Neuschatz
  • Paul L. Miller

Organizations

  • University of California

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  • Autonomy

DTIC Thesaurus Topics

  • Abstracts
  • Availability
  • California
  • Classification
  • Clone Cells
  • Computer Programs
  • Computers
  • Contracts
  • Data Sets
  • Immunoassay
  • Mainframe Computers
  • Military Research
  • New Jersey
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Fields of Study

  • Biology

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  • Computer Science/Computer Engineering/Data Science/Digital Signal Processing.
  • Database Systems and Applications
  • Molecular and Cellular Biochemistry

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  • AI & ML
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