Studies on Syntheses of Amine-Carboxyboranes (Boron Analogues of Amino Acids) and Derivatives.

Abstract

The principal goal of this research has been the synthesis and characterization of boron analogues of important biologically active molecules such as the amino acids. During this period of research synthesis were developed for esters and amides of a variety of simple boron analogues of amino acids. Also, routes to boron analogues of choline, acetylcholine and substituted acetylcholines were developed. Collaborative studies on the biological activity of many of these compounds were carried out by processor Iris H. Hall at University of North Carolina.

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Document Details

Document Type
Technical Report
Publication Date
Aug 17, 1987
Accession Number
ADA184838

Entities

People

  • Andrew T. McPhail
  • Bernard F. Spielvogel

Organizations

  • Duke University

Tags

DTIC Thesaurus Topics

  • Amines
  • Amino Acids
  • Analogs
  • Cholesteryl Esters
  • Classification
  • Contracts
  • Esters
  • Lipid Metabolism
  • Military Research
  • Molecular Structure
  • Molecules
  • Neutron Capture
  • New York
  • North Carolina
  • Security
  • Universities

Fields of Study

  • Chemistry

Readers

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