Detoxification of Acetylcholinesterase Inhibitors.
Abstract
The research support by ARO contract 212888-LS entitled Detoxification of acetylcholinesterase inhibitors has resulted in the cloning and partial sequence of two opd genes from Pseudomonas diminuta and Flavobacterium species. It has been possible to isolate the enzyme in association with a small membrane fraction and initiate e an evaluation of the organophosphate hydrolase. Collaborative interactions with research scientists at the Chemical Defense Research Command have suggested that the Pseudomonas species is competent to degrade selected types of biological neurotoxins.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 19, 1987
- Accession Number
- ADA184892
Entities
People
- James R. Wild
Organizations
- Texas A&M University