Experimental Third Degree Frostbite in Hanford Miniature Swine

Abstract

Third degree frostbite was produced in five Hanford Miniature Swine exposed to chilled air. Biopsies were taken. The 200 slides were evaluated microscopically: epithelial necrosis and regeneration were recorded as absent or present. Vascular degeneration, thrombosis, sweat gland injury, and subcutis injury were ranked. Epithelial necrosis and/or regeneration were seen consistently, but not until 1-2 weeks after injury. Vascular injury was absent for the 1 minute freeze, but was seen by 48 hours for the 5, 10, and 20 minute freezes. Sweat gland injury was seen by 12 hours for all freezes except the 1 minute freeze. Subcutis changes were seen 1-2 weeks after injury.

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Document Details

Document Type
Technical Report
Publication Date
Jul 06, 1987
Accession Number
ADA184981

Entities

People

  • Murray P. Hamlet
  • Polly Schoning

Organizations

  • United States Army Research Institute of Environmental Medicine

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Availability
  • Biological Sciences
  • Body Regions
  • Classification
  • Engineering
  • Frostbite
  • Laboratory Animals
  • Massachusetts
  • Military Research
  • Necrosis
  • Security
  • Skin
  • Sweat Glands
  • Thrombosis
  • Tissues
  • Universities

Fields of Study

  • Medicine

Readers

  • Thermal Physics or Thermal Science.
  • Trauma Surgery or Emergency Medicine.