Phosphoprotein Regulation of Synaptic Reactivity.

Abstract

This grant provided equipment for multi-user, multi-tasking minicomputer (VAX 11-750) and a cluster of micro-computers (IBM-XT) to support a DoD funded this research project investigated the regulation of neurobiological responsiveness. High speed digitization of neurophysiological signals and their analysis were performed on-line using IBM-XT installed A-D conversions. In our research program we seek to determine how the phosphorylation state of identified brain proteins regulates inter-synaptic changes in communication between nerve cells, monitored electrophysiologically at the synapse using microelectrodes.

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Document Details

Document Type
Technical Report
Publication Date
Aug 31, 1987
Accession Number
ADA185688

Entities

People

  • Aryeh Routtenberg

Organizations

  • Northwestern University

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Biological Sciences
  • Chemical Warfare Agents
  • Chemistry
  • Computers
  • Data Acquisition
  • Data Storage Systems
  • Fatty Acids
  • Gel Electrophoresis
  • Instrumentation
  • Kinases
  • Membrane Proteins
  • Midrange Computers
  • Neurons
  • Oleic Acid
  • Proteins
  • Regulations
  • Two Dimensional

Readers

  • Computer Science/Computer Engineering/Data Science/Digital Signal Processing.
  • Neuroscience
  • Oceanography.