Influence of Polycythemia on Blood Volume and Thermoregulation during Exercise-Heat Stress

Abstract

We studied the effects of autologous erythrocyte infusion on blood volume and thermoregulation during exercise in the heat. Nine unacclimated male subjects were infused with either 600 ml of a sodium chloride-glucose-phosphate solution containing a approx 50% hematocrit or 600 ml of this solution only. A heat stress test (HST was attempted approx 2-wk pre- nd 48-h postinfusion during the late spring months. The following observations were made: the increased Erythrocyte volume was associated with a reduction in plasma volume to maintain the same blood volume as during the preinfusion measurements: polycythemia reduced total circulating protein but did not alter F-cell ratio, plasma osmolality, plasma protein content, or plasma lactate at rest or during exercise-heat stress; polycythemia did not change the volume of fluid entering the intravascular space from rest to exercise-heat stress; and polycythemia tended to reduce the rate of heat storage during exercise-heat stress.

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1987
Accession Number
ADA185734

Entities

People

  • Andrew J Young
  • Michael N. Sawka
  • Richard C. Dennis
  • Richard R. Gonzalez
  • Stephen R. Muza

Organizations

  • United States Army Research Institute of Environmental Medicine

Tags

DTIC Thesaurus Topics

  • Blood
  • Blood Proteins
  • Blood Volume
  • Erythrocytes
  • Polycythemia
  • Proteins
  • Sodium Compounds
  • Stress Tests
  • Temperature Control
  • Volume

Readers

  • Exercise and Sports Science.
  • Immunology

Technology Areas

  • Space
  • Space - Hall-Effect Thruster