Differential Effects of Chronic Partial Myelotomies on Monoamine Levels in Cat Spinal Cord
Abstract
The concentrations of 5-hydroxytryptamine (5-HT), norepinephrine (NE) adn dopamine (DA) were measured in samples of lumbar and cervical spinal cords from 6 cats with chronic (over 2 months) lesions of the thoracic spinal cord and from 7 unoperated cats. Lesions confined to the dorsal thoracic spinal cord significantly lowered lumbar concentrations of NE, but not 5-HT, compared with control lumbar or matched paired cervical samples. Both NE and 5-HT were significantly reduced by dorsal or ventral lesions that involved tissue ventral canal. Only the largest lesion could be shown to reduce lumbar DA concentration.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1987
- Accession Number
- ADA187315
Entities
People
- Kenneth L. Casey
- L. C. Terry
- Ronald Craig
- Thomas J. Morrow
Organizations
- University of Michigan