Toxic Effects of Man-Made Mineral Fibers with Particular Reference to Ceramic Fibers
Abstract
In order to evaluate the potential hazards of man made mineral fibers (MMMF); particularly ceramic fibers, in the Navy work environment, the following areas are considered. First, the current standards and recommendations of other agencies are presented as an overview of current concensus as to relative hazards of asbestos, MMMF, and cristobalite (a form of crystalline silica). Then, a summary of recent epidemiological evidence is presented. These data should be the most relevant for human exposure. Unfortunately, there are no data for workers in the ceramic fiber field. Then a review is presented of the data from animal experiments which employed exposure by inhalation, intratracheal instillation, and intrapleural or intraperitoneal injection. The experiments reviewed involve only non-ceramic MMMF. Some detail of the protocol and results of each experiment are presented to provide a better understanding of the non- uniformity of the protocols used. Another issue of particular importance in understanding fiber toxicity is the durability of the fiber. These data are presented for non ceramic MMMF. Keywords: Adenoma, Carcinoma, Ceramic fibers, Chrysotile, Cristobalite, Crocidolite, Durability, Fibrosis, Fibrous glass, Glass wool, Inhalation, Intraperitoneal injection, Intrapleural injection.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1987
- Accession Number
- ADA187949
Entities
People
- Allen Vinegar