Analysis of Trichothecene Mycotoxins by Combined HPLC/MS.

Abstract

The development of HPLC/MS assays for the analysis of selected trichothecene mycotoxins in urine is the goal of this program. T-2 toxin has been the initial target of this investigation. Three important issues have been addressed before proceeding with the actual HPLC/MS experiments: the synthesis of isotopically labelled internal standards, efficient recovery of the target compounds from the urine matrix, and determination of HPLC conditions for their separation. Keywords: Mass spectrometry, High performance liquid chromatography, Phytotoxins.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Apr 15, 1986
Accession Number
ADA188700

Entities

People

  • B. L. Karger
  • Paul Vouros

Organizations

  • Northeastern University

Tags

DTIC Thesaurus Topics

  • Alcohols
  • Anhydrides
  • Chemical Analysis
  • Chemical Synthesis
  • Chemistry
  • Detection
  • Fungi
  • Hydroxides
  • Liquid Chromatography
  • Mass Spectra
  • Mass Spectrometers
  • Mass Spectrometry
  • Plastic Explosives
  • Recovery
  • Spectrometry
  • Standards
  • Water

Readers

  • Organic Chemistry
  • Political Science/ International Relations/ European Studies
  • Toxicology/Environmental Toxicology