Studies of the Biology of Phleboviruses in Sandflies.

Abstract

Investigations were carried out on the biology of phlebotomus fever group viruses (Bunyaviridae: Phlebovirus) in their sandfly vectors. This work included studies on the susceptibility of sandflies to oral and parenteral infection with phleboviruses, replication of the viruses in the insects, and the ability of these agents to be vertically transmitted in their vectors. In addition, a number of sandfly species were colonized for the first time, and two continuous sandfly cell cultures were established. Results of these studies suggest some phleboviruses are maintained in nature by two mechanisms: vertical (transovarial) transmission in their insect vector and an alternating mammal-insect cycle. Keywords: Virus diseases; Disease vectors; Entomology; Transmittance; Cultures(Biology); Cells(Biology).

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Document Details

Document Type
Technical Report
Publication Date
Aug 31, 1987
Accession Number
ADA189145

Entities

People

  • Robert B. Tesh

Organizations

  • Yale University

Tags

DTIC Thesaurus Topics

  • Arboviruses
  • Bunyaviridae
  • Cell Line
  • Cells
  • Culture Techniques
  • Encephalitis
  • Infection
  • Medical Personnel
  • Phlebotomus Fever
  • Rift Valley Fever
  • Rna Viruses
  • Ticks
  • Virus Diseases
  • Viruses
  • Zoonoses

Fields of Study

  • Biology

Readers

  • Vector-Borne Disease and Entomology
  • Virology (or Medical Virology).