Characterization and Modeling of Thoraco-Abdominal Response to Blast Waves. Volume 5. Experimental Investigation of Lung Injury Mechanism

Abstract

Edema formation is the most evident injury of the lung when it is subjected to an impact load. A quantitative evaluation of the lung injury is of interest. In this report we describe a gravimetric method which is based on first establishing an isogravimetric condition of the lung before the impact load is applied. Excised rabbit lung was tested. The total lung weight was measured continuously so that the rate of progress of edema was obtained. The edema rate provides a quantitative measure of lung injury. It is shown that the rate of edema formation depends on the rigidity of the surface on which the lung rested. If the lung was freely supported on a lightweight soft cloth the edema produced by and impact was much less than that produced in the same lung supported on a rigid plate. This undoubtedly indicates that the reflection of a stress wave on a hard surface imposes a more severe condition for lung injury. It is also shown that the initial velocity of impact at the surface of the lung is a principal parameter to correlate with the rate of edema formation after impact. Keywords: Wounds and injuries.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1985
Accession Number
ADA189671

Entities

People

  • M. R. Yen
  • Y. C. Fung

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Blast Loads
  • Blast Waves
  • Blood Vessels
  • Cardiovascular Physiological Phenomena
  • Classification
  • Dynamic Pressure
  • Impact Loads
  • Lung Diseases
  • Materials
  • Mechanical Properties
  • Security
  • Shock Tubes
  • Shock Waves
  • Stress Waves
  • Wave Propagation
  • Wounds And Injuries

Readers

  • Combustion Dynamics and Shock Wave Physics.
  • Immunology and Pathology
  • Systems Analysis and Design