Study of IL1 Structure Activity Relationship by Mass Spectrometry.

Abstract

The initial studies outlined in this report demonstrate that Biemann's approach to the sequencing of polypeptides by gas chromatography-mass spectrometry can be carried out on the bench top gas chromatograph-mass spectrometer - data system developed by Hewlett Packard. This technique has been used to determine the complete primary structure of glucagon and 50% of the primary structure of Tumor Necrosis Factor.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1987
Accession Number
ADA189941

Entities

People

  • J. W. Cowens

Organizations

  • Health Research, Incorporated

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Biological Sciences
  • Chemical Reactions
  • Chemical Synthesis
  • Chemistry
  • Chromatographs
  • Chromatography
  • Gas Chromatography
  • Mass Spectra
  • Mass Spectrometers
  • Mass Spectrometry
  • Materials
  • Materials Science
  • Peptides
  • Spectrometers
  • Spectrometry
  • Standards

Fields of Study

  • Chemistry

Readers

  • Aerospace Test and Evaluation
  • Analytical Chemistry
  • Molecular and Cellular Biochemistry