Genetic and Serological Analysis of Salmonella-coli Phage Hybrids and Development of New Mutator Phages with Expanded Host Ranges.

Abstract

Hybrids between Salmonella phage P22 and coli mutator phage Mu have been isolated, using their common hosts Escherichia coli - S. typhimurium recombinants. Although these evolutionary distant phages P22 and Mu have no genetic homology and totally different gene organizations and genomic structures, hybrids were found at an extremely low frequency. The MuimmP22 hybrid class carriers the entire late genes of Mu and some early genes at least the c region of P22. P22 grows in strains lysogenic for MuimmP22 though it carries the c region of P22. Keywords: Genetics; Gene mapping.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1987
Accession Number
ADA191630

Entities

People

  • Nobuto Yamamoto

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Acquisition
  • Bacteriophages
  • Classification
  • Escherichia Coli
  • Extremely Low Frequency
  • Frequency
  • Genes
  • Genetic Phenomena
  • Genetics
  • Immunity
  • Mutations
  • Neutralization
  • Observation
  • Orientation (Direction)
  • Salmonella Phages
  • Security

Fields of Study

  • Biology

Readers

  • Microbial Pathology
  • Molecular and genetic basis of cancer.

Technology Areas

  • Biotechnology