Acute Dermal Toxicity Potential of the Holston Compounds: Virgin DMSO, DMSO Recycle Solvent, and DMSO Evaporator Sludge in Male and Female Rabbits

Abstract

The acute dermal toxicity potential of the Holston Compounds (Virgin DMSO, DMSO Recycle Solvent, and DMSO Evaporator Sludge) was determined in rabbits by topical application to skin sites with plastic covering over the exposed areas for 24 hours. There were no compound-related deaths at a limit dose of 2 ml/kg during this study. The Holston Compounds caused minimal dermal irritation. Keywords: Explosives; Recrystallization; Neurotoxins; Solvents.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1984
Accession Number
ADA191793

Entities

People

  • Craig W. White
  • Glen E. Marrs
  • Lawrence Mullen

Organizations

  • Letterman Army Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Bandages
  • Biological Sciences
  • Biomedical Research
  • Chemical Analysis
  • Detectors
  • Epidermis
  • Flow Rate
  • Hair
  • Health Services
  • Liquid Chromatography
  • Materials
  • Medical Personnel
  • Military Research
  • Quarantine
  • Rdx
  • Toxicity
  • Toxicology

Readers

  • Agricultural Chemistry/Soil Science
  • Environmental Engineering.
  • Toxicology/Environmental Toxicology