Validation of a Modified One-Step Rebreathing Technique for Non-Invasive Measurement of Submaximal Cardiac Output

Abstract

The primary objectives of this study were to modify the Farhi one-step carbon dioxide (CO2) rebreathing technique for measuring cardiac output during rest and submaximal exercise, and then to validate our modifications. The novelty of Farhi's technique is that it (1) requires only one-step to acquire all data necessary for computations, (2) is noninvasive, (3) takes less than 30 seconds for each rebreathing maneuver, (4) can be repeated at rapid intervals (1-2 minutes), and (5) is accurate and highly reproducible. Because a low flow rate analyzer (mass spectrometer) that Farhi specified as being essential for monitoring CO2 at the mouth during rebreathing was available to us only on a limited basis and is not readily field portable, we modified both available equipment and technique. Keywords: Carbon dioxide rebreathing; Cardiac output; Noninvasive; Pulmonary blood flow.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1988
Accession Number
ADA192852

Entities

People

  • Ingrid V. Sils
  • Karleyton C. Evans
  • Patricia C. Szlyk

Organizations

  • United States Army Research Institute of Environmental Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biological Sciences
  • Blood Flow
  • Carbon Dioxide
  • Cardiovascular System
  • Classification
  • Computer Programming
  • Computer Programs
  • Computers
  • Data Science
  • Flow Rate
  • Heart Rate
  • Information Science
  • Mass Spectrometers
  • Measurement
  • Military Research
  • Respiration
  • Sampling

Readers

  • Analytical Chemistry
  • Cardiovascular Physiology
  • Computational Modeling and Simulation