Development and Testing of Living Skin Equivalent.

Abstract

Histology of grafts on recipient rat for up to 24 months showed that the matrix basket-weave pattern established at one month became more pronounced at one year. No hypertrophic scarring was observed in any skin-equivalent graft made although grafts of epidermis alone on a collagen bed without cells did result in scarring. Hypertrophy of the epidermis lessened between one month and one year, and at two years no hypertrophy was observed. Keywords: Isografts, Collagens, Fibroblasts, Wounds, Skin grafts, Skin(Anatomy), Skin substitutes. (kt)

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1988
Accession Number
ADA195784

Entities

People

  • Eugene Bell

Organizations

  • Massachusetts Institute of Technology

Tags

Communities of Interest

  • Air Platforms

DTIC Thesaurus Topics

  • Allografts
  • Anhydrides
  • Animals
  • Autografts
  • Blood Vessels
  • Cells
  • Collagen
  • Connective Tissue
  • Epidermis
  • Epithelial Cells
  • Epithelium
  • Fish
  • Laboratory Animals
  • Rodents
  • Skin
  • Tissues
  • Transplants

Fields of Study

  • Medicine

Readers

  • Molecular Biology and Genetics
  • Molecular and Cellular Biology
  • Polymer Science and Technology