Genetic and Molecular Studies of the Phlebotomus Fever Group of Viruses.

Abstract

Evidence has been obtained that Punta Toro (PT) virus, a member of the Phlebotomus fever serogroup of viruses (Phleboviruses, Bunyavidirae) has 3 virion RNA species (large, L, medium, M, and small, S), which are comparable in number to those of other members of the Bunyaviridae family, but different in size by comparison to the size of the S RNA of Bunyavirus genus members of the family. Studies supported by this grant report the coding strategies of the PT viral M and S RNA species and the characterization of their MRNA species. The amino terminal sequences of the G1 and G2 proteins have been mapped to the viral RNA sequence and the data compared to the M RNA sequence information of the Rift valley fever (RVF) virus obtained by USAMRIID staff and other contractees (Dr M. Collett). Keywords: Virus vaccines. (kt)

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Document Details

Document Type
Technical Report
Publication Date
Feb 10, 1988
Accession Number
ADA195817

Entities

People

  • David H. Bishop

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Antigens
  • Biomedical Research
  • Bunyaviridae
  • Civilian Personnel
  • Genetic Code
  • Infection
  • Infectious Diseases
  • Medical Personnel
  • Phlebotomus Fever
  • Proteins
  • Rift Valley Fever
  • Rift Valleys
  • Rna Viruses
  • Vaccines
  • Virology
  • Viruses

Fields of Study

  • Biology

Readers

  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology