Infectious Multiple Drug Resistance in the Enterobacteriaceae

Abstract

A new quantitative assay for the determination of E. coli heat-stable enterotoxin has been developed which is about 10-fold more sensitive than existing methods. A strategy for the development of subunit vaccines has been tested using specific peptides of the binding region of cholera toxin. Although there have been numerous reports of the relationship between E. coli LT toxin (and cholera toxin) and a putative enterotoxin of Salmonella typhimurium, we have been unable to demonstrate any DNA sequence homology between known sequences of E. coli LT, ST or cholera toxin with the nucleic acid of Salmonella.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1983
Accession Number
ADA195915

Entities

People

  • Stanley Falkow

Organizations

  • Stanford University

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Bioassay
  • Biological Factors
  • Biomedical And Dental Materials
  • Chemical Synthesis
  • Chemistry
  • Diseases And Disorders
  • Escherichia
  • Escherichia Coli
  • Immune Serums
  • Intestines
  • Microbiology
  • Molecular Weight
  • Nucleotides
  • Polymeric Films
  • Proteins
  • Vaccines

Fields of Study

  • Biology

Readers

  • Immunology
  • Molecular Genetics

Technology Areas

  • Biotechnology