Cardiopulmonary Effects of Acute Stressful Exercise at Altitude (2300m) of Individuals with Sickle Cell Trait (SCT)
Abstract
The possible health hazards for persons with Sickle Cell Trait (SCT) when engaged in strenuous exercise and/or environmental hypoxia is not fully defined. During Phase I and II (Annual Reports No. 1, 1985 and No. 2, 1986) of our Sickle Cell Trait research studies, no significant differences were found in the physiological response and exercise performance to acute strenuous exercise at 1,270 m and at simulated altitude of 2,300 m. During Phase III the following studies were carried out: Physiologic response to acute strenuous exercise during inspiratory hypoxia equivalent to 4000m in SCT; Interlaboratory variability of hemoglobin s levels (% HbS) in sickle cell trait; Lower single breath carbon monoxide diffusing capacity (DLCO) in black subjects compared to caucasians; and Basilic venous blood during progressive one-arm exercise. Keywords: Hemoglobin AS; Stress(Physiology); Cardiovascular system; Pulmonary function; Sickle cell trait.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 1987
- Accession Number
- ADA196460
Entities
People
- Idelle M. Weisman
- R. J. Zeballos
- Timothy W. Martin