Neuronal Mechanisms of Intelligence
Abstract
Equipment Acquired is described. All equipment has been used for on- line experimental control, data collection, and data analysis functions. In this work, we are investigating the adaptive rules used by mammalian brain cells in the mediation of intelligent behavior. The research is basd on the assumption that human intelligence has evolved from the goal-seeking brain functions of lower forms, and that these functions in turn depend on a capacity for behavior to be strengthened or rewarded by its consequences (positive reinforcement). We furthermore assume that positive reinforcement of the intact organism is physiologically mediated at the level of the single neuron, rather than at the level of the multi-neuronal assembly or network. The equipment is being used in the performance of experiments designed to investigate whether individual cellular activity can be reinforced by locally applied electrical or chemical stimulation, and, reinforcements. Experiments are being conducted on single neurons in cell culture, brain tissue slices, and intact brain. The instrumentation enabled us to investigate modification of ionic channels and cellular biochemistry related to reinforcement. In addition, the equipment was used for detailed data analysis and computer modeling.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 04, 1988
- Accession Number
- ADA196592
Entities
People
- Larry Stein
Organizations
- University of California, Irvine