Renal Medullary Solute Depletion Resulting from Psychogenic Polydipsia in a Rhesus Monkey
Abstract
A 9-year-old 9-kg male rhesus monkey was observed to have polydipsia and an unthrifty appearance. The monkey was being fed a commercial primate ration, with fresh water provided ad libitum by automatic waterer and was housed in individual caging. Physical examination revealed extensive bilateral periorbital edema and patchy alopecia over the lower trunk and limbs. Blood cell counts were unremarkable, but serum biochemical analysis revealed hyponatremia and hypochloremia. The only environmental alteration recorded for this monkey was a change in feeding regimen. The monkey had been inadvertantly fed almost twice his daily requirement of biscuits for nearly 4 months, resulting in obesity. Four weeks before the onset of polydipsia, the diet was restricted to 100% of the calculated daily caloric requirement, to diminish further unnecessary weight gain. This apparently was the triggering factor for the polydipsia. A water deprivation test resulted in an increase in urine specific gravity. The normal response to water deprivation verified a normal concentrating ability and the diagnosis of psychogenic polydipsia with renal medullary solute depletion. One year after diagnosis and treatment, there was no evidence of recurrent polydipsia. Keywords: Veterinary medicine, Reprints.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1988
- Accession Number
- ADA196774
Entities
People
- John G. Golden
- John W. Fanton
- Tony D. David
Organizations
- United States Air Force School of Aerospace Medicine