A Comparative Evaluation of Some Ortho Directing Groups for Cubane
Abstract
We have carried out a computational assessment of the relative ortho directing powers of four different functional groups in terms of their tendencies to interact with an adjacent lithium substituent, thereby producing a channel of strongly negative electrostatic potential leading to the lithiated (ortho) carbon. In terms of the factors examined in this analysis, it appears that the nitro group should have at least a moderate ortho-directing capability.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1988
- Accession Number
- ADA196826
Entities
People
- Jack Alster
- Keerthi Jayasuriya
- Peter Politzer
Organizations
- University of New Orleans