Functional Reconstitution of Olfactory Receptor for Analytical Application
Abstract
A model system has been used to study the initial electrochemical membrane events in chemoreception by the mammalian olfactory epithelium: Membrane from rat olfactory epithelial homogenates incorporated into planar biomolecular lipid membranes and patch-bilayers. Data has been obtained to support a hypothesis that the above described system in which it has been demonstrated the presence of ion selective channels coupled with an activated enzyme cascade bears functional relationship to the initial chemoreceptive steps in olfaction. Keywords: Ion channels; Membranes biology; Receptor sites; Active sites; Smell; Olfactory receptors; Olfactory systems; Olfactory epithelium; Chemoreception; Olfaction.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1988
- Accession Number
- ADA197042
Entities
People
- Vitaly Vodyanoy
Organizations
- University of California, Irvine