Multi-Order Calibration
Abstract
Instruments that generate two-dimensional arrays of data are now commonplace in the analytical laboratory. Time decay and emission-excitation fluorescence, chromatography-spectroscopy combinations, MS-MS and 2D-NMR, are a few of the many so-called 'hyphenated methods' that generate such data. These instruments have become very important for the analyst mainly because of their higher selectivity and resolution of signals, allowing for analysis of mixtures. The main similarity between all these instruments is that each sample analyzed produces a two-dimensional array of data (second order tensor). The amount of information produced by such an instrument is overwhelming; for quantitative analysis usually only a small portion of the data is actually used and the rest discarded. This paper will summarize a multi-order, tensorial approach to calibration, that takes advantage of all the information from instruments that produce data arrays of any order, for prediction of unknown properties such as analyte concentrations.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1988
- Accession Number
- ADA197534
Entities
People
- Bruce R. Kowalski
- Eugenio Sanchez
Organizations
- University of Washington