Characterization of Bovine Brain ATPase

Abstract

The purified bovine brain ATPase has been shown to be a high- affinity, low capacity pump, and consists of two proteins. A labile, high affinity dihydropyridine receptor activity has been associated with this ATPase activity. This study has shown that the purified (Ca2+ + Mg2+)-dependent ATPase can be immobilized, and that changes can be detected on the surface as increases in phosphate released and/or capacitance differences after interaction of the complex with a test ligand.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1988
Accession Number
ADA198212

Entities

People

  • James J. Valdes
  • James P. Chambers

Organizations

  • University of Texas at San Antonio

Tags

Communities of Interest

  • Advanced Electronics
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Anhydrides
  • Capacitance
  • Capacitance Bridges
  • Cell Membrane
  • Cellular Structures
  • Chemical Analysis
  • Chemistry
  • Chromatography
  • Laboratory Animals
  • Liquid Chromatography
  • Molecular Weight
  • Nucleosides
  • Nucleotides
  • Polysaccharides
  • Protons
  • Sugar Alcohols
  • Synapses

Fields of Study

  • Biology

Readers

  • Molecular and Cellular Biochemistry