Biochemical Mechanisms controlling Bioreactivity of Adrenal Chromaffin Cells
Abstract
This project has examined the biochemical mechanisms regulating the response of the rat adrenal medulla and chromaffin tissue. The responsitivity of the tissue will change depending upon the treatment that the animal has received and the time after the treatment. The alteration in reactivity appears to be correlated with changes in tissue levels of the catecholamine neurotransmitters. Tissues that demonstrate altered reactivity have profound morphological changes that return to control with the return of normal reactivity. Additional biochemical factors that may regulate reactivity are currently being examined in a variety of model systems of the chromaffin cell. Keywords: Adrenal gland, Chromaffin cells, Phosphorylation, Stress, Molecular mechanisms, Monoclonal antibodies.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 17, 1988
- Accession Number
- ADA198471
Entities
People
- P. R. Vulliet
Organizations
- Colorado State University