Acute Dermal Toxicity Potential of Guanidine Nitrate in Male and Female Rabbits

Abstract

The acute dermal toxicity of guanidine nitrate was determined in rabbits by topical application to skin sites with a semiocclusive covering for 24 hours. No compound-related deaths or clinical signs were observed at a limit dose of 2 g/kg during this study; however, guanidine nitrate did produce dermal irritation under conditions of the study. Keywords: Guanidine nitrate, Acute dermal toxicity, Rabbits, Nitroguanidine, Munitions.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1988
Accession Number
ADA198494

Entities

People

  • Don W. Korte Jr.
  • Steven K. Sano

Organizations

  • Letterman Army Hospital

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Ear Diseases
  • Fungi
  • Guanidine Nitrates
  • Health
  • Health Services
  • Materials
  • Medical Personnel
  • Munitions
  • New Zealand
  • Pathology
  • Security
  • Toxicity
  • Toxicology
  • Triple Base Propellants
  • United States

Readers

  • Toxicology/Environmental Toxicology