Progress on the Synthesis of Facially Hindered Metallobenzporphyrins

Abstract

Reaction of isoindole, benzaldehyde and zinc acetate at 400 C has been shown to be a useful synthesis of zinc meso-tetraphenyltetrabenzporphyrin. We have repeated this reaction using mesitaldehyde (2,4,6-trimethylbenzadehyde) in place of benzaldehyde. Proton NMR analysis of the product indicates that only partial substitution of mesityl groups in the meso positions has occurred. This is contrasted with the reaction of pyrrole and mesitaldehyde in the presence of boron trifluoride etherate followed by treatment with chloranil to yield meso-tetramesitylporphyrin. Attempts to extend this synthesis to the tetrabenzporphyrins by using isoindole in place of pyrrole were unsuccessful. Keywords: Porphyrins, Tetrabenzporphyrins, Meso-substituted porphyrins, Synthesis, NMR spectroscopy.

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Document Details

Document Type
Technical Report
Publication Date
Jul 12, 1988
Accession Number
ADA198784

Entities

People

  • D. E. Remy
  • J. W. Cullen

Organizations

  • United States Army Soldier Systems Center

Tags

Communities of Interest

  • Air Platforms

DTIC Thesaurus Topics

  • 2-Ring Heterocyclic Compounds
  • Availability
  • Benzaldehydes
  • Chemical Warfare
  • Chemical Warfare Agents
  • Classification
  • Engineering
  • High Temperature
  • Hydrogen
  • Liquid Chromatography
  • Materials
  • Organic Materials
  • Porphyrins
  • Security
  • Silica Gels
  • Systems Biology
  • Thermal Instability

Fields of Study

  • Chemistry

Readers

  • Organic Chemistry