Characterization of African Human Retroviruses Related to HTLV-III/LAV

Abstract

Seroepidemiologic surveys conducted in Africa have demonstrated infection with HIV-2 in most West African nations surveyed. There appears to be little overlap with geographic regions reporting high rates of HIV-1 infection and AIDS. Seroprevalence for HIV-2 is 2-8 fold higher in sexually active groups demonstrating that similar to HIV-1 this virus is also sexually transmitted. Although high rates of HIV-2 infection can be seen in some West African populations the number of AIDS cases is still quite low suggesting a distinct pathobiology to this new human retrovirus. Cohort studies of HIV-2 infected individuals have also failed to demonstrate progression to clinical symptomatology associated with AIDS in an African setting. Keywords: Immunosuppression; Viruses; Serology; Epidemiology; Virus diseases.

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Document Details

Document Type
Technical Report
Publication Date
Jun 15, 1988
Accession Number
ADA199785

Entities

People

  • Phyllis J. Kanki

Organizations

  • Harvard T.H. Chan School of Public Health

Tags

DTIC Thesaurus Topics

  • Africa
  • Antigens
  • Blood
  • Blood Donors
  • Blood Transfusions
  • Cells
  • Diseases And Disorders
  • Genetic Code
  • Health Services
  • Infection
  • Ivory Coast
  • Laboratory Animals
  • Proteins
  • Public Health
  • United States
  • West Africa
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Infectious Disease/Epidemiology
  • International Relations, focusing on Korea-Africa and North Korea-South Korea relations, and Nigeria-Latin American Relations.