Sickle-Cell Trait as a Risk Factor for Sudden Death in Physical Training

Abstract

Case reports of sudden death during exertion have not established an association between the sickle-cell trait (hemoglobin AS) and exercise-related death. To test this association, all deaths occurring among 2 million enlisted recruits during basic training in the U.S. Armed Forces in 1977 to 1981 were classified from autopsy and clinical records as non-sudden deaths or as sudden deaths explained or unexplained by preexisting disease. we conclude that recruits in basic training with the sickle-cell trait have a substantially increased, age dependent risk of exercise-related sudden death unexplained by any known preexisting cause. Reprints.

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Document Details

Document Type
Technical Report
Publication Date
Sep 24, 1987
Accession Number
ADA199932

Entities

People

  • Charles J. Ruehle
  • David M. Posey
  • Harold R. Schumacher
  • John A. Kark

Organizations

  • Walter Reed Army Institute of Research

Tags

DTIC Thesaurus Topics

  • Basic Training
  • Cells
  • Classification
  • Confidence Limits
  • Death
  • Diseases And Disorders
  • Health Services
  • Heat Stroke
  • Hematologic Diseases
  • Hematology
  • Medical Personnel
  • Military Training
  • New England
  • Risk Factors
  • Sickle Cells
  • Statistical Analysis
  • Training

Fields of Study

  • Biology
  • Medicine

Readers

  • Cardiovascular Physiology
  • Marine Propulsion Engineering and Naval Architecture
  • Psychometric Testing or Psychological Assessment.