Bloodmeal Identification by Direct Enzyme-Linked Immunosorbent Assay (ELISA), Tested on Anopheles (Diptera: Culicidae) in Kenya

Abstract

BLOODMEAL identification for mosquitoes and other hematophagous Diptera is important in the study of malaria and other arthropod-borne disease. Several serological techniques have been used to detect host-specific blood meals. Of the available techniques, the precipitin test has been used most commonly. Enzyme-linked immunosorbent assays (ELISA) have been developed for bloodmeal identification and have proven useful for field studies. This study describes three techniques - a simple, direct ELISA to screen mosquitoes for human, cow, goat, pig, horse, and chicken blood meals; methods to test blood meals for two different hosts in the same microtiter plate well; and methods whereby the bloodmeal ELISA for sporozoites. Anopheles gambiae Giles s. lat. and Anopheles funestus Giles were collected and tested in Kenya to evaluate the ELISA assays. Reprints.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1988
Accession Number
ADA199936

Entities

People

  • Diana Diggs
  • John C. Beier
  • Joseph Koros
  • Peter V. Perkins
  • Robert A. Wirtz

Organizations

  • Walter Reed Army Institute of Research

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Arthropod Borne Diseases
  • Availability
  • Biomedical And Dental Materials
  • Biomedical Research
  • Dilution
  • Diseases And Disorders
  • Domestic
  • Filter Paper
  • Geographic Regions
  • Identification
  • Immune Serums
  • Immunoglobulins
  • Indicator Dyes
  • Malaria
  • Materials
  • Polymeric Films

Fields of Study

  • Biology

Readers

  • Immunology
  • Toxicology/Environmental Toxicology
  • Vector-Borne Disease and Entomology