Pharmacological Resetting of the Circadian Sleep-Wake Cycle

Abstract

Our research has seen the completion of several projects aimed at elucidating the chronopharmacological properties of benzodiazepines in rodents and monkeys, and at investigating the circadian and homeostatic mechanisms involved in the regulation of sleep in monkeys. We have also recently completed a series of studies on the neural control of circadian rhythms in the squirrel monkey. The results obtained thus far have several interesting implications, some of which are currently being tested. Keywords: Circadian rhythms; Circadian pacemaker; Suprachiasmatic nuclei; Triazolam; Diazepam; Rapid eye movement; Phase response curve; Phase shift; Reentrainment; Sleep deprivation; Homeostasis.

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Document Details

Document Type
Technical Report
Publication Date
Jun 30, 1988
Accession Number
ADA200246

Entities

People

  • M. C. Moore-ede

Organizations

  • Harvard Medical School

Tags

Communities of Interest

  • Advanced Electronics
  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Air Force
  • Animals
  • Biological Rhythms
  • Biological Sciences
  • Biology
  • Brain
  • Circadian Rhythms
  • Medical Personnel
  • Monkeys
  • Nervous System
  • Neurosciences
  • Phase Shift
  • Regulations
  • Rodents
  • Sleep Deprivation
  • Squirrel Monkeys

Fields of Study

  • Biology
  • Psychology

Readers

  • Circadian Sleep-Wake Regulation and Chronobiology
  • Neuroscience