Analysis and Synthesis of Adaptive Neural Elements and Assemblies
Abstract
The overall goal of this research is to provide insights into the adaptive capabilities of individual neurons, which will lead to the development of machines having some of the information processing capabilities of the nervous system. During the period between 01 August 1987 and 31 July 1988, significant progress has been in three major directions. First, a previous mathematical model of sensory neurons that exhibit adaptive plasticity has been extended to include more detailed descriptions of critical cellular processes. Second, a single-cell neuronal model for classical conditioning has been incorporated into a network and the capabilities of the network to simulate higher-order features of associative learning has been examined and analyzed. Third, experimental studies have been performed on individual neurons in order to examine the modulation of membrane currents and critical second messengers that are believed to contribute to neuronal plasticity and classical conditioning.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 22, 1988
- Accession Number
- ADA201239
Entities
People
- John H. Byrne
Organizations
- McGovern Medical School