Final Report on the International Narcotic Research Conference (16th) Held in North Falmouth, Massachusetts on 23-28 June 1985
Abstract
The meeting was held at the Seacrest Hotel, North Falmouth, Massachusetts, June 23-28, 1985. Several presentations on the isolation of the opiopeptin receptors revealed varying states of purity and indicated that the isolation of a purified receptor should be accomplished within the next year. Genomic and cDNA probes for the opiopeptin precursors were utilized to provide answers concerning the regulation of expression of the genes and their mRNAs, which cells express specific genes, and the pharmacologic treatments that act through gene expression. Additional cleavage loci of precursor proteins for yielding bioactive site and cleavage enzymes were identified. Although enkephalinase may lack specificity, it may be conveyed by selective distribution of the enzyme at sites where the peptides are located such as in the ventrolateral striatum.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 28, 1985
- Accession Number
- ADA201457
Entities
People
- E. L. Way
Organizations
- University of California, San Francisco