Brain Mechanisms Underlying Individual Differences in Reaction to Stress: An Animal Model

Abstract

The research described in this final report is designed to expand the animal model for augmenting-reducing in rats and cats. Much effort has been put into developing an acute preparation in which VEPs variability is maintained at a manageable level. A two pronged effort is used to determine the neural mechanisms underlying augmenting-reducing. First, laminar origins of the components of VEPs. With this information, anatomical and physiological knowledge of visual cortex can be used to narrow down the putative mediators for this phenomenon. Second, determination of the effect of electrical and chemical lesions and electrical stimulation of subcortical nuclei on VEPs can be used to attempt ot experimentally control the mechanisms that produce augmenting- reducing.

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Document Details

Document Type
Technical Report
Publication Date
Oct 29, 1988
Accession Number
ADA201595

Entities

People

  • David F. Sisson
  • Jerone Siegel
  • Patricia M. Saxton

Organizations

  • University of Delaware

Tags

Communities of Interest

  • Human Systems
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Abstracts
  • Amplitude
  • Brain
  • Cerebral Cortex
  • Electrophysiological Phenomena
  • Frequency
  • Human Behavior
  • Intensity
  • Medical Personnel
  • Military Research
  • Peripheral Nervous System
  • Personality
  • Power Spectra
  • Psychophysiology
  • Scientists
  • Security
  • Visual Cortex

Readers

  • Neuroscience
  • Theoretical Analysis.
  • Vision Science/Vision Psychology/Cognitive Neuroscience.