Effects of He-O2 Breathing during Experimental Decompression Sickness Following Air Dives
Abstract
The effects of ventilation with helium -diatomic oxygen during decompression sickness (DCS) and venous air embolism were studied. Fifteen anesthetized dogs were mechanically ventilated and subjected to repeated air dives until pulmonary artery pressure at least doubled within 10 min postdive. At 30 min postdive, ventilation was either continued with air (controls, n=7 or changed to He-O2(n = 8) for an additional 90 min. All animals developed pulmonary hypertension, systemic hypotension, hemoconcentration, hypoxemia, hypercarbia, and pulmonary edema. Breathing air or He-O2 postdive did not alter the responses, but He-O2 breathing produced in 11% increase in pulmonary vascular resistance (PVR). In 3 other anesthetized dogs that were not subjected to dives, ventilation was changed to He-O2 at various times during an intravenous infusion of air; He-O2 breathing caused a 22% increase in PVR. We conclude that breathing He-O2 during DCS resulting from an air dive can intensify pulmonary vascular obstruction. Reprints.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 1987
- Accession Number
- ADA201774
Entities
People
- E. T. Flynn Jr.
- J. J. Mcdermott
- L. B. Thomas
- M. A. Holt
- P. W. Catron
Organizations
- Naval Medical Research Center