Observations on Hospitalized Dengue Patients
Abstract
Between Oct 31, 1983 and Mar 31, 1984, 379 dengue cases were confirmed at the Hospital of Infant Jesus. Most (77.6%) of the patients were 10 years and below, but only 2 cases were infants. 26 (6.8%) showed a primary antibody response while 322 (84.9%) had a secondary antibody response. 3 serotypes of dengue virus were recovered: 13 Den 3, 12 Den 1 & 6 Den 2 strains. Anorexia, flushing, vomiting, hepatomegaly and abdominal pain were the most frequent nonspecific findings. The most common hemorrhagic manifestations were positive tourniquet test, petechiae, & epistaxis. Shock was recorded in 33 cases, 2 of which were fatal. Correlation of antibody response to severity of disease showed that petechiae and GI bleeding were more frequent in cases with a secondary type of response. All cases of shock that could be classified serologically had a secondary antibody response. This study shows that dengue infection remains a common cause of hospitalization among children in Manila. Hospitalization is apparently more commonly associated with secondary infection. Reprints.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1987
- Accession Number
- ADA201871
Entities
People
- Corazon D. Leus
- Corazon R. Manaloto
- Curtis G. Hayes
- Rolando S. Songco
Organizations
- Naval Medical Research Center