Malaria Sporozoite Penetration: A New Approach by Double Straining

Abstract

To determine, whether a sporozoite is outside the hepatocyte membrane or internalized, a double staining test was carried out using, successively, antibody labeled with peroxidase and fluorescein. This test permits the quantification of sporozoite entry and outline sporozoite-hepatocyte interactions. Keywords: Malaria; Double staining test; Sporozoite; Hepatocyte; Culture; Reprints.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1988
Accession Number
ADA202173

Entities

People

  • Dominique Mazier
  • Francois Miltgen
  • Jan P. Verhave
  • Laurent Renia
  • Thivi Ponnudurai
  • William E. Collins
  • Yupin Charoenvit

Organizations

  • Naval Medical Research Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alcohols
  • Antibodies
  • Biological Staining And Labeling
  • Biomedical Research
  • Blood
  • Blood Cells
  • Cells
  • Diseases And Disorders
  • Epithelial Cells
  • Fluorophores
  • Infectious Diseases
  • Laser Dyes
  • Malaria
  • Materials
  • Parasites
  • Proteins
  • Spores

Fields of Study

  • Education

Readers

  • Materials Science (Mechanical Engineering).
  • Molecular and Cellular Biochemistry
  • Parasitology and Pharmacology of Malaria.