Target Oriented Drugs against Leishmania

Abstract

Our first annual report has demonstrated the presence of very high galactose content in EF, a property that could be shared also by the surface carbohydrates of the parasite. EF has immunological properties similar to those of the intact parasite and may play a role in the infective process. After it was shown to be species-specific, EF became the basis for serotyping Leishmania strains, and is a valuable tool in diagnostic, demographic and ecological studies of the disease. The diagnostic methodology, however, is generally insufficient and the development of a reliable radioimmunoassay (RIA) seems most valuable.

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Document Details

Document Type
Technical Report
Publication Date
Oct 26, 1981
Accession Number
ADA203670

Entities

People

  • Joseph El-on
  • Uri Zehavi

Organizations

  • Hebrew University of Jerusalem

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amino Acids
  • Antibodies
  • Biochemistry
  • Biomedical Research
  • Blood
  • Carbohydrates
  • Cells
  • Chemistry
  • Immune Serums
  • Leishmania
  • Leishmaniasis
  • Macrophages
  • Medical Personnel
  • Molecular Weight
  • Precipitation
  • Sodium Compounds
  • Sugars

Fields of Study

  • Medicine

Readers

  • Analytical Chemistry
  • Infectious Disease/Epidemiology
  • Software Engineering.